Suppression of Gonadotropins and Estradiol in Premenopausal Women by Oral Administration of the Nonpeptide Gonadotropin-Releasing Hormone Antagonist Elagolix

Context: Parenteral administration of peptide GnRH analogs is widely employed for treatment of endometriosis and fibroids and in assisted-reproductive therapy protocols. Elagolix is a novel, orally available nonpeptide GnRH antagonist. Objective: Our objective was to evaluate the safety, pharmacokin...

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Autors principals: Struthers, R. Scott, Nicholls, Andrew J., Grundy, John, Chen, Takung, Jimenez, Roland, Yen, Samuel S. C., Bozigian, Haig P.
Format: Artigo
Idioma:Inglês
Publicat: The Endocrine Society 2009
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2646513/
https://ncbi.nlm.nih.gov/pubmed/19033369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2008-1695
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