Excess circulating angiopoietin-2 is a strong predictor of mortality in critically ill medical patients

INTRODUCTION: The endothelial specific angiopoietin (Ang)-Tie2 ligand-receptor system has been identified as a non-redundant mediator of endothelial activation in experimental sepsis. Binding of circulating Ang-1 to the Tie2 receptor protects the vasculature from inflammation and leakage, whereas bi...

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Main Authors: Kümpers, Philipp, Lukasz, Alexander, David, Sascha, Horn, Rüdiger, Hafer, Carsten, Faulhaber-Walter, Robert, Fliser, Danilo, Haller, Hermann, Kielstein, Jan T
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2646310/
https://ncbi.nlm.nih.gov/pubmed/19025590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/cc7130
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