Involvement of Angiopoietin-2 and Tie2 Receptor Phosphorylation in STEC-HUS Mediated by Escherichia coli O104:H4

Escherichia coli O104:H4-associated hemolytic uremic syndrome (HUS) is characterized by Shiga toxin-induced vascular damage. As indicated by recent studies, dysregulation of the angiopoietin (Angpt)/Tie2 ligand receptor system may be crucial for endothelial dysfunction in HUS. Early Angpt-2 levels q...

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Bibliographic Details
Published in:Mediators Inflamm
Main Authors: Lukasz, Alexander, Beneke, Jan, Thamm, Kristina, Kielstein, Jan T., Menne, Jan, Mikesch, Jan-Henrik, Schmidt, Bernhard M. W., Haller, Hermann, Kümpers, Philipp, David, Sascha, Schiffer, Mario
Format: Artigo
Language:Inglês
Published: Hindawi Publishing Corporation 2015
Subjects:
Clinical Study
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4706916/
https://ncbi.nlm.nih.gov/pubmed/26858516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/670248
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