Singular value decomposition-based regression identifies activation of endogenous signaling pathways in vivo

The ability to detect activation of signaling pathways based solely on gene expression data represents an important goal in biological research. We tested the sensitivity of singular value decomposition-based regression by focusing on functional interactions between the Ras and transforming growth f...

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Hauptverfasser: Liu, Zhandong, Wang, Min, Alvarez, James V, Bonney, Megan E, Chen, Chien-chung, D'Cruz, Celina, Pan, Tien-chi, Tadesse, Mahlet G, Chodosh, Lewis A
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2008
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2646284/
https://ncbi.nlm.nih.gov/pubmed/19094238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2008-9-12-r180
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