Application of Bayesian regression with singular value decomposition method in association studies for sequence data

Genetic association studies usually involve a large number of single-nucleotide polymorphisms (SNPs) (k) and a relative small sample size (n), which produces the situation that k is much greater than n. Because conventional statistical approaches are unable to deal with multiple SNPs simultaneously...

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Detalhes bibliográficos
Main Authors: Kwon, Soonil, Yan, Xiaofei, Cui, Jinrui, Yao, Jie, Yang, Kai, Tsiang, Donald, Li, Xiaohui, Rotter, Jerome I, Guo, Xiuqing
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Proceedings
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3287895/
https://ncbi.nlm.nih.gov/pubmed/22373181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1753-6561-5-S9-S57
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