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Reverse engineering gene networks using singular value decomposition and robust regression

We propose a scheme to reverse-engineer gene networks on a genome-wide scale using a relatively small amount of gene expression data from microarray experiments. Our method is based on the empirical observation that such networks are typically large and sparse. It uses singular value decomposition t...

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Detalhes bibliográficos
Main Authors: Yeung, M. K. Stephen, Tegnér, Jesper, Collins, James J.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC122920/
https://ncbi.nlm.nih.gov/pubmed/11983907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.092576199
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