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Targeting of Aryl Hydrocarbon Receptor-Mediated Activation of Cyclooxygenase-2 Expression by the Indole-3-Carbinol Metabolite 3,3′-Diindolylmethane in Breast Cancer Cells

Ligands of the aryl hydrocarbon receptor (AhR) include the environmental xenobiotic 2,3,7,8 tetrachlorodibenzo(p)dioxin (TCDD), polycyclic aryl hydrocarbons, and the dietary compounds 3, 3′-diindolylmethane (DIM), a condensation product of indol-3-carbinol found in Brassica vegetables, and the phyto...

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Главные авторы: Degner, Stephanie C., Papoutsis, Andreas J., Selmin, Ornella, Romagnolo, Donato F.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Nutrition 2009
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2646210/
https://ncbi.nlm.nih.gov/pubmed/19056653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3945/jn.108.099259
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