Endoplasmic Reticulum Stress Is Reduced in Tissues of Obese Subjects After Weight Loss

OBJECTIVE—Obesity is associated with insulin resistance and type 2 diabetes, although the mechanisms linking these pathologies remain undetermined. Recent studies in rodent models revealed endoplasmic reticulum (ER) stress in adipose and liver tissues and demonstrated that ER stress could cause insu...

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Autors principals: Gregor, Margaret F., Yang, Ling, Fabbrini, Elisa, Mohammed, B. Selma, Eagon, J. Christopher, Hotamisligil, Gökhan S., Klein, Samuel
Format: Artigo
Idioma:Inglês
Publicat: American Diabetes Association 2009
Matèries:
Pathophysiology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2646068/
https://ncbi.nlm.nih.gov/pubmed/19066313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db08-1220
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