Gene Silencing of Phogrin Unveils Its Essential Role in Glucose-Responsive Pancreatic β-Cell Growth

OBJECTIVE—Phogrin and IA-2, autoantigens in insulin-dependent diabetes, have been shown to be involved in insulin secretion in pancreatic β-cells; however, implications at a molecular level are confusing from experiment to experiment. We analyzed biological functions of phogrin in β-cells by an RNA...

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Bibliografiska uppgifter
Huvudupphovsmän: Torii, Seiji, Saito, Naoya, Kawano, Ayumi, Hou, Ni, Ueki, Kohjiro, Kulkarni, Rohit N., Takeuchi, Toshiyuki
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Diabetes Association 2009
Ämnen:
Islet Studies
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2646067/
https://ncbi.nlm.nih.gov/pubmed/19073770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db08-0970
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