Muscle-Derived Angiopoietin-Like Protein 4 Is Induced by Fatty Acids via Peroxisome Proliferator–Activated Receptor (PPAR)-δ and Is of Metabolic Relevance in Humans

OBJECTIVE— Long-chain fatty acids (LCFAs) contribute to metabolic homeostasis in part via gene regulation. This study's objective was to identify novel LCFA target genes in human skeletal muscle cells (myotubes). RESEARCH DESIGN AND METHODS— In vitro methods included culture and treatment of hu...

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Detalhes bibliográficos
Main Authors: Staiger, Harald, Haas, Carina, Machann, Jürgen, Werner, Roman, Weisser, Melanie, Schick, Fritz, Machicao, Fausto, Stefan, Norbert, Fritsche, Andreas, Häring, Hans-Ulrich
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2009
Assuntos:
Metabolism
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2646056/
https://ncbi.nlm.nih.gov/pubmed/19074989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db07-1438
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