Muscle-Derived Angiopoietin-Like Protein 4 Is Induced by Fatty Acids via Peroxisome Proliferator–Activated Receptor (PPAR)-δ and Is of Metabolic Relevance in Humans

OBJECTIVE— Long-chain fatty acids (LCFAs) contribute to metabolic homeostasis in part via gene regulation. This study's objective was to identify novel LCFA target genes in human skeletal muscle cells (myotubes). RESEARCH DESIGN AND METHODS— In vitro methods included culture and treatment of hu...

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Hlavní autoři: Staiger, Harald, Haas, Carina, Machann, Jürgen, Werner, Roman, Weisser, Melanie, Schick, Fritz, Machicao, Fausto, Stefan, Norbert, Fritsche, Andreas, Häring, Hans-Ulrich
Médium: Artigo
Jazyk:Inglês
Vydáno: American Diabetes Association 2009
Témata:
Metabolism
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2646056/
https://ncbi.nlm.nih.gov/pubmed/19074989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db07-1438
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