Activation of Cytosolic Phospholipase A(2)-α as a Novel Mechanism Regulating Endothelial Cell Cycle Progression and Angiogenesis

Release of endothelial cells from contact-inhibition and cell cycle re-entry is required for the induction of new blood vessel formation by angiogenesis. Using a combination of chemical inhibition, loss of function, and gain of function approaches, we demonstrate that endothelial cell cycle re-entry...

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Detalhes bibliográficos
Main Authors: Herbert, Shane P., Odell, Adam F., Ponnambalam, Sreenivasan, Walker, John H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Lipids and Lipoproteins: Metabolism, Regulation, and Signaling
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2645829/
https://ncbi.nlm.nih.gov/pubmed/19119141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M807282200
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