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A VE-cadherin–PAR3–α-catenin complex regulates the Golgi localization and activity of cytosolic phospholipase A(2)α in endothelial cells

Phospholipase A(2) enzymes hydrolyze phospholipids to liberate arachidonic acid for the biosynthesis of prostaglandins and leukotrienes. In the vascular endothelium, group IV phospholipase A(2)α (cPLA(2)α) enzyme activity is regulated by reversible association with the Golgi apparatus. Here we provi...

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書誌詳細
主要な著者: Odell, Adam F., Hollstein, Monica, Ponnambalam, Sreenivasan, Walker, John H.
フォーマット: Artigo
言語:Inglês
出版事項: The American Society for Cell Biology 2012
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オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3338442/
https://ncbi.nlm.nih.gov/pubmed/22398721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E11-08-0694
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