Mechanistic Insight into Control of CFTR by AMPK

The cystic fibrosis transmembrane conductance regulator (CFTR) is a cAMP and protein kinase A (PKA)-regulated Cl(–) channel in the apical membrane of epithelial cells. The metabolically regulated and adenosine monophosphate-stimulated kinase (AMPK) is colocalized with CFTR and attenuates its functio...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kongsuphol, Patthara, Cassidy, Diane, Hieke, Bernhard, Treharne, Kate J., Schreiber, Rainer, Mehta, Anil, Kunzelmann, Karl
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2009
Schlagworte:
Membrane Transport, Structure, Function, and Biogenesis
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2645823/
https://ncbi.nlm.nih.gov/pubmed/19095655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M806780200
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