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Energy landscape along an enzymatic reaction trajectory: hinges or cracks?
Are the most dynamically flexible regions around the equilibrium structure of an enzyme the same regions involved in the transition state for rate limiting processes involved in the enzymatic reaction? Kern and-coworkers (Wolf-Watzet al., 2004; Henzler-Wildman et al., 2007a, 2007b) have shown that i...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
HFSP Publishing
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2645576/ https://ncbi.nlm.nih.gov/pubmed/19404472 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2976/1.2894846 |
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