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α-Synuclein Conformation Affects its Tyrosine-Dependent Oxidative Aggregation
Oxidative stress and aggregation of the protein α-synuclein are thought to be key factors in Parkinson’s disease. Previous work shows that cytochrome c plus H(2)O(2) causes tyrosine-dependent in vitro peroxidative aggregation of proteins, including α-synuclein. Here, we examine the role of each of α...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2645542/ https://ncbi.nlm.nih.gov/pubmed/19049426 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi801884z |
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