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(19)F-NMR Studies of α-Synuclein Conformation and Fibrillation
Fibrils of the intrinsically-disordered protein α-synuclein are hallmarks of Parkinson's disease. The fluorescent dye thioflavin T is often used to characterize fibrillation, but this assay may not provide quantitative information about structure and mechanism. To gain such information, we inco...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2749620/ https://ncbi.nlm.nih.gov/pubmed/19655784 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi900872p |
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