Stretch-Induced Regulation of Angiotensinogen Gene Expression in Cardiac Myocytes and Fibroblasts: Opposing Roles of JNK1/2 and p38α MAP Kinases

The cardiac renin-angiotensin system (RAS) has been implicated in mediating myocyte hypertrophy, remodeling, and fibroblast proliferation in the hemodynamically overloaded heart. However, the intracellular signaling mechanisms responsible for regulation of angiotensinogen (Ao), a substrate of the RA...

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Main Authors: Lal, Hind, Verma, Suresh K., Golden, Honey B., Foster, Donald M., Smith, Manuela, Dostal, David E.
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2645232/
https://ncbi.nlm.nih.gov/pubmed/18926830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2008.09.121
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