Rac1 and RhoA differentially regulate angiotensinogen gene expression in stretched cardiac fibroblasts

AIMS: Angiotensin II (Ang II) stimulates cardiac remodelling and fibrosis in the mechanically overloaded myocardium. Although Rho GTPases regulate several cellular processes, including myocardial remodelling, involvement in mediating mechanical stretch-induced regulation of angiotensinogen (Ao), the...

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Detalhes bibliográficos
Main Authors: Verma, Suresh K., Lal, Hind, Golden, Honey B., Gerilechaogetu, Fnu, Smith, Manuela, Guleria, Rakeshwar S., Foster, Donald M., Lu, Guangrong, Dostal, David E.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3058736/
https://ncbi.nlm.nih.gov/pubmed/21131638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvq385
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