Phase I Study of ch14.18 With Granulocyte-Macrophage Colony-Stimulating Factor and Interleukin-2 in Children With Neuroblastoma After Autologous Bone Marrow Transplantation or Stem-Cell Rescue: A Report From the Children's Oncology Group

PURPOSE: Recurrence of high-risk neuroblastoma is common despite multimodality therapy. ch14.18, a chimeric human/murine anti-G(D2) antibody, lyses neuroblastoma cells. This study determined the maximum tolerable dose (MTD) and toxicity of ch14.18 given in combination with interleukin-2 (IL-2) after...

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Bibliografische gegevens
Hoofdauteurs: Gilman, Andrew L., Ozkaynak, M. Fevzi, Matthay, Katherine K., Krailo, Mark, Yu, Alice L., Gan, Jacek, Sternberg, Adam, Hank, Jacquelyn A., Seeger, Robert, Reaman, Gregory H., Sondel, Paul M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society of Clinical Oncology 2009
Onderwerpen:
Pediatric Oncology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2645092/
https://ncbi.nlm.nih.gov/pubmed/19047298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2006.10.3564
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