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The SET Complex Acts as a Barrier to Autointegration of HIV-1

Retroviruses and retrotransposons are vulnerable to a suicidal pathway known as autointegration, which occurs when the 3′-ends of the reverse transcript are activated by integrase and then attack sites within the viral DNA. Retroelements have diverse strategies for suppressing autointegration, but h...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Yan, Nan, Cherepanov, Peter, Daigle, Janet E., Engelman, Alan, Lieberman, Judy
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2644782/
https://ncbi.nlm.nih.gov/pubmed/19266025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000327
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