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MGLUR5 ACTIVATION INHIBITS MICROGLIAL ASSOCIATED INFLAMMATION AND NEUROTOXICITY

The group I metabotropic glutamate receptor 5 (mGluR5) can modulate addiction, pain and neuronal cell death. Expression of some mGluRs, such as group II and III mGluRs, has been reported in microglia and may affect their activation. However, the expression and role of mGluR5 in microglia is unclear....

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Detalhes bibliográficos
Main Authors: Byrnes, Kimberly R., Stoica, Bogdan, Loane, David J., Riccio, Angela, Davis, Margaret I., Faden, Alan I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2644739/
https://ncbi.nlm.nih.gov/pubmed/18816644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.20783
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