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Activation of Metabotropic Glutamate Receptor 5 Improves Recovery after Spinal Cord Injury in Rodents

OBJECTIVE: Activation of metabotropic glutamate receptor 5 (mGluR5) has neuroprotective properties in vitro and has been reported to limit postischemic lesion volume in vivo. Previously, mGluR5 has been identified on microglia in vitro, but the effects of mGluR5 activation on inflammation in vivo or...

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Detalhes bibliográficos
Main Authors: Byrnes, Kimberly R., Stoica, Bogdan, Riccio, Angela, Pajoohesh-Ganji, Ahdeah, Loane, David J., Faden, Alan I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3755738/
https://ncbi.nlm.nih.gov/pubmed/19670441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.21673
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