Activation of Metabotropic Glutamate Receptor 5 Improves Recovery after Spinal Cord Injury in Rodents

OBJECTIVE: Activation of metabotropic glutamate receptor 5 (mGluR5) has neuroprotective properties in vitro and has been reported to limit postischemic lesion volume in vivo. Previously, mGluR5 has been identified on microglia in vitro, but the effects of mGluR5 activation on inflammation in vivo or...

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Bibliografiske detaljer
Main Authors: Byrnes, Kimberly R., Stoica, Bogdan, Riccio, Angela, Pajoohesh-Ganji, Ahdeah, Loane, David J., Faden, Alan I.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3755738/
https://ncbi.nlm.nih.gov/pubmed/19670441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.21673
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