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Combined use of mass spectrometry and heterologous expression for identification of membrane-interacting peptides in cytochrome P450 46A1 and NADPH-cytochrome P450 oxidoreductase

Cytochrome P450 46A1 (CYP46A1) and NADPH-cytochrome P450 oxidoreductase (CPR) are the components of the brain microsomal mixed-function monooxygenase system that catalyzes the conversion of cholesterol to 24-hydroxycholesterol. Both CYP46A1 and CPR are monotopic membrane proteins that are anchored t...

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Bibliografske podrobnosti
Main Authors: Mast, Natalia, Liao, Wei-Li, Pikuleva, Irina A., Turko, Illarion V.
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2644731/
https://ncbi.nlm.nih.gov/pubmed/19161969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2009.01.002
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