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Synthesis, characterization and development of a high-throughput methodology for the discovery of botulinum neurotoxin A inhibitors

Botulinum neurotoxins (BoNTs), etiological agents of the deadly food poisoning disease botulism, are the most toxic proteins currently known. Although only a few hundred cases of botulism are reported in the United States annually, there is growing interest in BoNTs attributable to their potential u...

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Hlavní autoři: Boldt, Grant E., Kennedy, Jack P., Hixon, Mark S., McAllister, Laura A., Barbieri, Joseph T., Tzipori, Saul, Janda, Kim D.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2644723/
https://ncbi.nlm.nih.gov/pubmed/16827563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cc060010h
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