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β(1) integrins differentially control extravasation of inflammatory cell subsets into the CNS during autoimmunity
Inhibiting the α(4) subunit of the integrin heterodimers α(4)β(1) and α(4)β(7) with the monoclonal antibody natalizumab is an effective treatment for multiple sclerosis (MS). However, the pharmacological action of natalizumab is not understood conclusively. Previous studies suggested that natalizuma...
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| Auteurs principaux: | , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2009
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2644139/ https://ncbi.nlm.nih.gov/pubmed/19179279 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0808909106 |
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