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α(4)β(1) Integrin Mediates the Recruitment of Immature Dendritic Cells across the Blood-Brain Barrier during Experimental Autoimmune Encephalomyelitis

Dendritic cells (DCs) within the CNS are recognized to play an important role in the effector phase and propagation of the immune response in experimental autoimmune encephalomyelitis (EAE), a mouse model for multiple sclerosis. However, the mechanisms regulating DC trafficking into the CNS still ne...

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Detalhes bibliográficos
Main Authors: Jain, Pooja, Coisne, Caroline, Enzmann, Gaby, Rottapel, Robert, Engelhardt, Britta
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3999618/
https://ncbi.nlm.nih.gov/pubmed/20483748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0901404
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