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Fluids and barriers of the CNS establish immune privilege by confining immune surveillance to a two-walled castle moat surrounding the CNS castle

Neuronal activity within the central nervous system (CNS) strictly depends on homeostasis and therefore does not tolerate uncontrolled entry of blood components. It has been generally believed that under normal conditions, the endothelial blood-brain barrier (BBB) and the epithelial blood-cerebrospi...

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Autors principals: Engelhardt, Britta, Coisne, Caroline
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3039833/
https://ncbi.nlm.nih.gov/pubmed/21349152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2045-8118-8-4
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