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Fluids and barriers of the CNS establish immune privilege by confining immune surveillance to a two-walled castle moat surrounding the CNS castle

Neuronal activity within the central nervous system (CNS) strictly depends on homeostasis and therefore does not tolerate uncontrolled entry of blood components. It has been generally believed that under normal conditions, the endothelial blood-brain barrier (BBB) and the epithelial blood-cerebrospi...

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Detalhes bibliográficos
Main Authors: Engelhardt, Britta, Coisne, Caroline
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3039833/
https://ncbi.nlm.nih.gov/pubmed/21349152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2045-8118-8-4
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