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A model for DNA replication showing how dormant origins safeguard against replication fork failure

Replication origins are ‘licensed' for a single initiation event before entry into S phase; however, many licensed replication origins are not used, but instead remain dormant. The use of these dormant origins helps cells to survive replication stresses that block replication fork movement. Her...

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Bibliografische gegevens
Hoofdauteurs: Blow, J Julian, Ge, Xin Quan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2009
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2644062/
https://ncbi.nlm.nih.gov/pubmed/19218919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2009.5
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