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Deletion of hepatic Ctr1 reveals its function in copper acquisition and compensatory mechanisms for copper homeostasis

Copper is a vital trace element required for normal growth and development of many organisms. To determine the roles for copper transporter 1 (Ctr1) in hepatic copper metabolism and the contribution of the liver to systemic copper homeostasis, we have generated and characterized mice in which Ctr1 i...

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Detalhes bibliográficos
Main Authors: Kim, Heejeong, Son, Hwa-Young, Bailey, Sarah M., Lee, Jaekwon
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2643901/
https://ncbi.nlm.nih.gov/pubmed/19095764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.90632.2008
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