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The Role of Ctr1 and Ctr2 in Mammalian Copper Homeostasis and Platinum-based Chemotherapy

Copper (Cu) is an essential metal for growth and development that has the potential to be toxic if levels accumulate beyond the ability of cells to homeostatically balance uptake with detoxification. One system for Cu acquisition is the integral membrane Cu(+) transporter, Ctr1, which has been quite...

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Detalhes bibliográficos
Main Authors: Öhrvik, Helena, Thiele, Dennis J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4175275/
https://ncbi.nlm.nih.gov/pubmed/24703712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtemb.2014.03.006
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