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Impaired insulin-mediated vasorelaxation in diabetic Goto-Kakizaki rats is caused by impaired Akt phosphorylation

Insulin resistance associated with Type 2 diabetes contributes to impaired vasorelaxation. Previously, we showed the phosphorylation of myosin-bound phosphatase substrate MYPT1, a marker of the vascular smooth muscle cell (VSMC) contraction, was negatively regulated by Akt (protein kinase B) phospho...

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Detalhes bibliográficos
Main Authors: Lee, Jin Hee, Palaia, Thomas, Ragolia, Louis
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2643848/
https://ncbi.nlm.nih.gov/pubmed/19052261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00254.2008
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