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The C-Terminal Domain of Cernunnos/XLF Is Dispensable for DNA Repair In Vivo
The core nonhomologous end-joining DNA repair pathway is composed of seven factors: Ku70, Ku80, DNA-PKcs, Artemis, XRCC4 (X4), DNA ligase IV (L4), and Cernunnos/XLF (Cernunnos). Although Cernunnos and X4 are structurally related and participate in the same complex together with L4, they have distinc...
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Main Authors: | , , , , , , |
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Format: | Artigo |
Language: | Inglês |
Published: |
American Society for Microbiology (ASM)
2009
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Subjects: | |
Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2643816/ https://ncbi.nlm.nih.gov/pubmed/19103754 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01521-08 |
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