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The C-Terminal Domain of Cernunnos/XLF Is Dispensable for DNA Repair In Vivo

The core nonhomologous end-joining DNA repair pathway is composed of seven factors: Ku70, Ku80, DNA-PKcs, Artemis, XRCC4 (X4), DNA ligase IV (L4), and Cernunnos/XLF (Cernunnos). Although Cernunnos and X4 are structurally related and participate in the same complex together with L4, they have distinc...

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Bibliographic Details
Main Authors: Malivert, Laurent, Callebaut, Isabelle, Rivera-Munoz, Paola, Fischer, Alain, Mornon, Jean-Paul, Revy, Patrick, de Villartay, Jean-Pierre
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2009
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2643816/
https://ncbi.nlm.nih.gov/pubmed/19103754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01521-08
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