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DNA Genome Size Affects the Stability of the Adenovirus Virion
Replication-defective adenovirus (Ad) vectors can vary considerably in genome length, but whether this affects virion stability has not been investigated. Helper-dependent Ad vectors with a genome size of ∼30 kb were 100-fold more sensitive to heat inactivation than their parental helper virus (>...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Society for Microbiology (ASM)
2009
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2643769/ https://ncbi.nlm.nih.gov/pubmed/19036812 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01644-08 |
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