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Level of Herpes Simplex Virus Type 1 Latency Correlates with Severity of Corneal Scarring and Exhaustion of CD8(+) T Cells in Trigeminal Ganglia of Latently Infected Mice

A hallmark of infection with herpes simplex virus type 1 (HSV-1) is the establishment of latency in ganglia of the infected individual. During the life of the latently infected individual, the virus can occasionally reactivate, travel back to the eye, and cause recurrent disease. Indeed, a major cau...

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Detalhes bibliográficos
Main Authors: Mott, Kevin R., Bresee, Catherine J., Allen, Sariah J., BenMohamed, Lbachir, Wechsler, Steven L., Ghiasi, Homayon
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2643740/
https://ncbi.nlm.nih.gov/pubmed/19091870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02234-08
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