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Mutational Analysis of a Conserved Glutamic Acid Required for Self-Catalyzed Cross-Linking of Bacteriophage HK97 Capsids

The capsid of bacteriophage HK97 is stabilized by ∼400 covalent cross-links between subunits which form without any action by external enzymes or cofactors. Cross-linking only occurs in fully assembled particles after large-scale structural changes bring together side chains from three subunits at e...

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Autors principals: Dierkes, Lindsay E., Peebles, Craig L., Firek, Brian A., Hendrix, Roger W., Duda, Robert L.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2643733/
https://ncbi.nlm.nih.gov/pubmed/19091865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02000-08
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