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Crosslinking renders bacteriophage HK97 capsid maturation irreversible and effects an essential stabilization

In HK97 capsid maturation, structural change (‘expansion') is accompanied by formation of covalent crosslinks, connecting residue K169 in the ‘E-loop' of each subunit with N356 on another subunit. We show by complementation experiments with the K169Y mutant, which cannot crosslink, that cr...

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Detalhes bibliográficos
Main Authors: Ross, Philip D, Cheng, Naiqian, Conway, James F, Firek, Brian A, Hendrix, Roger W, Duda, Robert L, Steven, Alasdair C
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1142538/
https://ncbi.nlm.nih.gov/pubmed/15775971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600613
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