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Crosslinking renders bacteriophage HK97 capsid maturation irreversible and effects an essential stabilization
In HK97 capsid maturation, structural change (‘expansion') is accompanied by formation of covalent crosslinks, connecting residue K169 in the ‘E-loop' of each subunit with N356 on another subunit. We show by complementation experiments with the K169Y mutant, which cannot crosslink, that cr...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2005
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1142538/ https://ncbi.nlm.nih.gov/pubmed/15775971 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600613 |
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