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A Free Energy Cascade with Locks Drives Assembly and Maturation of Bacteriophage HK97 Capsid.
We investigated the thermodynamic basis of HK97 assembly by scanning calorimetry and cryo-electron microscopy. This pathway involves self-assembly of hexamers and pentamers of the precursor capsid protein gp5 into procapsids; proteolysis of their N-terminal Δdomains; expansion - a major conformation...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1941702/ https://ncbi.nlm.nih.gov/pubmed/17007875 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2006.08.048 |
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