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Predicting the Impact of Blocking Human Immunodeficiency Virus Type 1 Nef In Vivo

Human immunodeficiency virus type 1 (HIV-1) Nef is a multifunctional protein that confers an ability to evade killing by cytotoxic T lymphocytes (CTLs) as well as other advantages to the virus in vivo. Here we exploited mathematical modeling and related statistical methods to estimate the impact of...

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Autors principals: Wick, W. David, Gilbert, Peter B., Yang, Otto O.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2643708/
https://ncbi.nlm.nih.gov/pubmed/19091857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00821-08
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