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Functional Characterization of the Human Immunodeficiency Virus Type 1 Nef Acidic Domain

The human immunodeficiency virus type 1 (HIV-1) accessory protein Nef downregulates major histocompatibility complex class I (MHC-I) from the cell surface. It has been proposed that the direct interaction of the acidic cluster (AC) of Nef, (62)EEEE(65), with the furin binding region (fbr) of PACS-1...

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Detalhes bibliográficos
Main Authors: Baugh, Laura L., Garcia, J. Victor, Foster, John L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2546962/
https://ncbi.nlm.nih.gov/pubmed/18653452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00107-08
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