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Humanized Mouse Model of Cooley's Anemia
A novel humanized mouse model of Cooley's Anemia (CA) was generated by targeted gene replacement in embryonic stem (ES) cells. Because the mouse does not have a true fetal hemoglobin, a delayed switching human γ to β(0) globin gene cassette (γβ(0)) was inserted directly into the murine β globin...
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| Autors principals: | , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Biochemistry and Molecular Biology
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2643510/ https://ncbi.nlm.nih.gov/pubmed/19098001 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M805681200 |
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