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Update on the functional biology of Lrrk2
The etiology of Parkinson’s disease (PD) was long thought to be due to environmental factors. Following the discovery of autosomal-dominant mutations in the α-synuclein gene, and later recessive mutations in the DJ-1, Parkin and PINK-1 genes, the field of PD genetics exploded. In 2004, it was discov...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2008
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2643425/ https://ncbi.nlm.nih.gov/pubmed/19225574 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/14796708.3.6.669 |
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