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PKC phosphorylation of TRAF2 mediates IKKα/β recruitment and K63-linked polyubiquitination
Tumor necrosis factor (TNF) receptor-associated factor 2 (TRAF2) is a key mediator in TNF signaling. Previous studies suggested that TRAF2 functions as an adaptor in the NF-κB and AP-1 pathways. However, the precise molecular mechanisms by which TRAF2 relays signals are unknown. We previously report...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2643372/ https://ncbi.nlm.nih.gov/pubmed/19150425 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2008.11.023 |
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