Down-regulation of Enhancer of Zeste-2 decreases growth of estrogen receptor negative invasive breast carcinoma and requires BRCA1

Increased levels of EZH2, a critical regulator of cellular memory, are associated with negative estrogen receptor (ER) expression and disease progression in breast cancer. High levels of EZH2 signal the presence of metastasis and poor outcome in breast cancer patients. To test the hypothesis that de...

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Hlavní autoři: Gonzalez, Maria E., Li, Xin, Toy, Katherine, DuPrie, Matthew, Ventura, Alejandra C., Banerjee, Mousumi, Ljugman, Mats, Merajver, Sofia D., Kleer, Celina G.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2643353/
https://ncbi.nlm.nih.gov/pubmed/19079346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2008.433
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