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Increased thymus- and decreased parathyroid-fated organ domains in Splotch mutant embryos
Embryos that are homozygous for Splotch, a null allele of Pax3, have a severe neural crest cell (NCC) deficiency that generates a complex phenotype including spina bifida, exencephaly and cardiac outflow tract abnormalities. Contrary to the widely held perception that thymus aplasia or hypoplasia is...
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| Главные авторы: | , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2008
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2643307/ https://ncbi.nlm.nih.gov/pubmed/19135046 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2008.12.019 |
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