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Synergy between Natriuretic Peptides and Phosphodiesterase 5 Inhibitors Ameliorates Pulmonary Arterial Hypertension

Rationale: Phosphodiesterase 5 (PDE5) inhibitors (e.g., sildenafil) are selective pulmonary vasodilators in patients with pulmonary arterial hypertension. The mechanism(s) underlying this specificity remains unclear, but studies in genetically modified animals suggest it might be dependent on natriu...

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書誌詳細
主要な著者: Baliga, Reshma S., Zhao, Lan, Madhani, Melanie, Lopez-Torondel, Belen, Visintin, Cristina, Selwood, David, Wilkins, Martin R., MacAllister, Raymond J., Hobbs, Adrian J.
フォーマット: Artigo
言語:Inglês
出版事項: American Thoracic Society 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2643218/
https://ncbi.nlm.nih.gov/pubmed/18689467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.200801-121OC
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