Cigarette Smoke Induces Cellular Senescence via Werner's Syndrome Protein Down-regulation

Rationale: Werner's syndrome is a genetic disorder that causes premature aging due to loss-of-function mutations in a gene encoding a member of the RecQ helicase family. Both Werner's syndrome and cigarette smoking accelerate aging. No studies have examined the effect of cigarette smoke on...

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Hlavní autoři: Nyunoya, Toru, Monick, Martha M., Klingelhutz, Aloysius L., Glaser, Heather, Cagley, Jeffrey R., Brown, Charles O., Matsumoto, Eiyu, Aykin-Burns, Nukhet, Spitz, Douglas R., Oshima, Junko, Hunninghake, Gary W.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Thoracic Society 2009
Témata:
B. Chronic Obstructive Pulmonary Disease
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2643077/
https://ncbi.nlm.nih.gov/pubmed/19011155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.200802-320OC
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