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Mutations in the Chinese hamster ovary cell GART gene of de novo purine synthesis

Mutations in several steps of de novo purine synthesis lead to human inborn errors of metabolism often characterized by mental retardation, hypotonia, sensorineural hearing loss, optic atrophy, and other features. In animals, the phosphoribosylglycinamide transformylase (GART) gene encodes a trifunc...

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Bibliografiska uppgifter
Huvudupphovsmän: Knox, Aaron J., Graham, Christine, Bleskan, John, Brodsky, Gary, Patterson, David
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2008
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2643067/
https://ncbi.nlm.nih.gov/pubmed/19007868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gene.2008.10.007
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