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Characterization of a mutator gene in Chinese hamster ovary cells.

We have recently reported the isolation of a class of mutants (called thy-) that is both resistant to arabinosyl cytosine and auxotrophic for thymidine. thy- mutants have a 5- to 10-fold elevated pool of dCTP and are deficient in the synthesis of dTTP as an apparent consequence of a single mutation...

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Dettagli Bibliografici
Autori principali: Meuth, M, L'Heureux-Huard, N, Trudel, M
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1979
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC411894/
https://ncbi.nlm.nih.gov/pubmed/293738
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