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Selective Elimination of Autoreactive T cells in vivo by the Regulatory T Cells
How regulatory T cells (Treg) control autoreactive T cells has not been analyzed in animals with a normal T cell repertoire. Using endogenous viral superantigens (VSAg) as the primary self antigens and mice with the Scurfy mutation of FoxP3, we show here that the Treg defect causes preferential accu...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2008
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2643025/ https://ncbi.nlm.nih.gov/pubmed/18838339 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clim.2008.08.014 |
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